By the time she was 23, Mulholland had participated in more than fifty sit-ins and protests. She was a Freedom Rider, a participant in the near riotous Jackson, Mississippi Woolworth Sit-in, and helped plan and organize the March on Washington in 1963. On a local level, she was part of the first Arlington sit-ins, which integrated lunch counters across northern Virginia, and helped to coordinate demonstrations at Glen Echo Park, Bethesda's Hiser Theater amongst other locations.